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Immunohistological detection, quantification, and morphological characterization of dendritic spines in fixed brain samples.

Re-engineering Neurohistology
for CNS Drug Discovery

Expressive's unique approach means you get clearer results, faster.

High-resolution CNS histology showing nuclear and protein staining

We’re a full-service neurohistology company leveraging the power of informatics to return actionable results, on time.

"We have used Expressive Neuroscience for several projects and they always deliver high quality images and analysis in a timely manner.  Great partner for any immunohistochemistry projects!"

Greg Dillon, PhD

Biogen

We integrate expert tissue processing and advanced fluorescence microscopy protocols with machine learning and a proprietary data analysis platform to provide high-throughput, quantitative neurohistology.   Our unique approach provides our customers with important advantages over both traditional histology and non-histological methods

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Working with Expressive

Your Missions

Neurodegeneration
Rare CNS Disorders
Psychiatric Disorders
Stroke
Cancer
and Others

Typically 4-10 weeks

Your Modalities

Small Molecules
Gene Therapy
Antisense Oligos
Enzymes
Stem Cells
and Others
Our Measurements

Protein Quantification and Localization
Dendritic Spine Counts
Cell Morphology Assays
Informatics Analysis
and Others

Services:​

  • Experimental design
  • Animal study coordination
  • Sectioning
  • Immunohistology
  • Diolistic spine labeling
  • In situ RNA detection
  • Confocal and Airyscan imaging
  • Image analysis
  • Data analysis
  • Reporting
  • Consulting

 

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Expressive’s team has decades of combined experience in neuroscience and informatics. Let our experts help you get definitive answers. 

Expressive Neuroscience headquarters in Syracuse NY

Contact us to discuss how Expressive can accelerate your CNS therapeutic discovery.

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